Design, synthesis and initial characterisation of a radiolabelled [(18)F]pyrimidoindolone probe for detecting activated caspase-3/7.

An optimized activity-based probe for the study of caspase-6 activation.

Although significant efforts have been made to understand the mechanisms of caspase activation during apoptosis, many questions remain regarding how and when executioner caspases get activated. We describe the design and synthesis of an activity-based probe that labels caspase-3/-6/-7, allowing direct monitoring of all executioner caspases simultaneously. This probe has enhanced in vivo propert...

Synthesis of activated carbon/zinc oxide nanocomposite from rapeseed plant waste by green chemistry method, evaluation of its performance in Methylene Blue pigment removal and optimization of influencing parameters using design expert

Background and Objective: Due to the water shortages and the presence of industrial pollutants in water resources, wastewater treatment, especially colored wastewater, is essential. The aim of this study was to treat wastewater containing Methylene Blue dye using activated carbon nanocomposite/zinc oxide nanoparticles (ZnO/AC) obtained from canola oil waste by green method. Materials and Metho...

Experimental design and response surface modeling for optimization of humic substances removal by activated carbon: A kinetic and isotherm study

The presence of humic acid (HA) in water treatment processes is very harmful and the cause of undesirable color, taste, and smell. Drinking water containing high concentrations of humic substances can be the cause of many health problems. Therefore, the removal of these compounds from water resources is a very important topic. In this research, response surface methodology (RSM) has been used t...

Eliminating caspase-7 and cathepsin B cross-reactivity on fluorogenic caspase-3 substrates† †Electronic supplementary information (ESI) available: Supporting figures, synthesis and characterisation of the substrates, and enzymatic assays. See DOI: 10.1039/c5mb00730e Click here for additional data file.

Preparation and biochemical characterisation of nanoconjugates of functionalized carbon nanotubes and cytochrome c

Objective(s): The present work deals with the preparation of nanobioconjugates based on the immobilization of cytochrome c (cyt c) on functionalized multi-wall carbon nanotubes (f-MWCNTs). The effect of the nanosupport and the immobilization procedure on the biochemical and structural characteristics of the immobilized protein was investigated. Methods: </strong...